Abstract Currently, the UN General Assembly has officially initiated the process of developing an international legally binding instrument on the conservation and sustainable use of biodiversity beyond national jurisdiction. Regarded as the third implementing agreement of the United Nations Convention on the Law of the Sea, the instrument will cope with a series of important issues including high seas marine protected areas. In the earlier negotiation, the parties have not reached a consensus on the management model of the high seas protected areas. Based on an indepth analysis of both global and regional management model, limitations of the regional model on the issue of high seas marine protected areas could be concluded. In the followup negotiations, China should put forward corresponding measures on the basis of insisting on advocating the adoption of a global model so as to effectively promote negotiation on the issue of high seas marine protected areas.